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Comparison of the clinical effect of ropivacaine combined with different adjuvants in the treatment of transverse abdominal muscle plane block

Comparison of the clinical effect of ropivacaine combined with different adjuvants in the treatment of transverse abdominal muscle plane block

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400092689
Enrollment
Unknown
Registered
2024-11-21
Start date
2024-03-24
Completion date
Unknown
Last updated
2024-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Group A: TAPB group:TAPB formulation was ropivacaine
Group B: dexmedetomidine group:TAPB formula was ropivacaine combined with dexmedetomidine
Group C: dexamethasone group:TAPB formula was ropivacaine combined with dexamethasone
Group D: morphine group:TAPB formulation was ropivacaine combined with morphine.

Sponsors

The Third People's Hospital of Shenzhen
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Age 18-65 years old, ASA Grade I to II, BMI 18-30kg /m^2

Exclusion criteria

Exclusion criteria: History of allergy to narcotic drugs (such as ropivacaine, dexmedetomidine, dexamethasone, etc.) or other serious drugs; Endocrine diseases or diseases of the immune system; Preoperative treatment for endocrine disruption (such as radiotherapy or chemotherapy); The expected operation time is greater than 4 hours; Puncture site infection; Severe coagulation dysfunction; Preoperatively treated with opioids or have a mental illness that affects your pain score; Severe organ dysfunction before surgery; Combined with severe arrhythmia; The preoperative and postoperative evaluations could not be completed or the treating physician considered it unsuitable to participate in the study.

Design outcomes

Primary

MeasureTime frame
Resting visual analog score;

Secondary

MeasureTime frame
Total use of sufentanil after surgery;Plasma concentrations of inflammatory factors;

Countries

China

Contacts

Public ContactWu Qiang

The Third People's Hospital of Shenzhen

wq2283@qq.com+86 186 2007 0099

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026