Liver cancer
Conditions
Sponsors
The First Affiliated Hospital of Guangzhou University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: Sex: any gender, BMI 18-30 kg/m^2, age: 18-64 years, ASA class I-III, Child ? Pugh class A or B, volunteering to participate in the study and signing an informed consent form.
Exclusion criteria
Exclusion criteria: pregnancy or lactation; known allergy to any drug used in the study; haemoglobin (Hb) 30 kg/m2 or 180 mmHg, or even > 180 mmHg in primary hypertension without taking any medication; liver function classification > Child- Pugh B, renal function abnormalities (creatine, Cr > 178 µmol/ L); severe organic lesions in vital organs such as heart and kidney; previous history of liver surgery; mental illnesses that prevented simple communication and cooperation in completing the experiments; and severe dysfunction in blood coagulation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative complications; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraoperative blood loss;Heart Rate;central venous pressure (CVP);cardiac output index (CI);stroke volume variation;Liver section haemorrhage score;Intraoperative norepinephrine administration;Serum lactate;Alaninetransaminase ALT ;Aspartate aminotransferase AST;Creatinine Cr ;Incidence of postoperative complications;Days in hospital;MAP(mean arterial pressure);SystolicBloodPressure SBP;Diastolic Blood Pressure DBP;Malondialdehyde MDA;Superoxide dismutase,SOD ;interleukin- 6 IL- 6; | — |
Countries
China
Contacts
Public ContactWuhua Ma
The First Affiliated Hospital of Guangzhou University of Chinese Medicine
Outcome results
None listed