intrauterine adhesion
Conditions
Interventions
control group (Intrauterine adhesion separation):None
experimental group (Autologous platelet-rich plasma and intrauterine adhesion separation):None
Sponsors
Shanghai Sixth People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients treated with intrauterine adhesion separation alone or combined with PRP; 2, moderate to severe IUA (AFS score =5); 3, have fertility requirements; 4, age between 20-40 years old; 5. Normal endocrine and ovulation functions 6, no fertility requirements, but the reduction of menstrual volume =50% or amenorrhea, considering uterine factors, has excluded other causes (such as central factors, decreased ovarian function, ovulation disorders, etc.) caused
Exclusion criteria
Exclusion criteria: 1. Contraindications for hysteroscopic surgery; 2, estrogen and progesterone treatment contraindications; 3, pregnancy contraindications; 4, have other uterine diseases, such as endometritis, severe adenomyopathy or submucosal myoma; 5. History of pelvic malignancy and radiotherapy; 6. Dysfunction of liver, kidney, heart, lung and other vital organs; 7. Clinical manifestations of blood diseases, such as platelet dysfunction or severe anemia; 8, there are other infertility factors, such as early-onset ovarian failure, polycystic ovarian syndrome or early-onset ovarian insufficiency; 9, inflammation of the reproductive organs, such as endometritis, vaginitis, acute or subacute cervicitis, acute and chronic pelvic inflammation, reproductive tract tuberculosis, sexually transmitted diseases, untreated and untreated; 10. Abnormal uterine bleeding did not exclude endometrial lesions; 11. Body temperature higher than 37.5 degrees
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The decline of AFS and IUA scores and the rate of adhesion reconstruction were compared between the two groups.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes of postoperative menstrual flow;Postoperative endometrial thickness changes;Clinical pregnancy rate; | — |
Countries
China
Contacts
Public ContactHaiyan Hu
Shanghai Sixth People's Hospital
Outcome results
None listed