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Application of collagen matrix biofilm in the maintenance of keratinized gingiva after immediate implant placement in posterior teeth: a prospective randomized controlled study

Application of collagen matrix biofilm in the maintenance of keratinized gingiva after immediate implant placement in posterior teeth: a prospective randomized controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400092652
Enrollment
Unknown
Registered
2024-11-21
Start date
2024-12-01
Completion date
Unknown
Last updated
2024-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Soft tissue deficiency

Interventions

Experimental group:Keratinized gingiva maintenance during Immediate implantation with collagen matrix biofilm in posterior sites
Control group:None

Sponsors

Zhejiang Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: (1) Patients aged =18 years with no history of systemic diseases; (2) the posterior teeth without preservation value (3) The buccal bone wall of the extraction socket was intact after extraction (4) no infection of soft tissue wound; (5) Patients had good compliance (6) agree to participate in this clinical trial and sign the informed consent.

Exclusion criteria

Exclusion criteria: (1) Acute infection of affected teeth or adjacent teeth and soft tissues; (2) female patients during pregnancy or lactation; (3) taking drugs affecting platelet or bone regeneration within 3 months; (4) patients with a history of head and neck radiotherapy and uncontrolled systemic diseases; (5) heavy smokers, smoking more than 10 cigarettes/day.

Design outcomes

Primary

MeasureTime frame
Keratinized gingival width at 6 months after surgery;

Secondary

MeasureTime frame
Changes in alveolar bone height and width at 6 months after surgery;

Countries

China

Contacts

Public ContactFan Yang

Zhejiang Provincial People's Hospital

yangfan@hmc.edu.cn+86 571 8589 3206

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026