The effect of lung recruitment maneuvers combined with individualized positive end-expiratory pressure on perioperative hemodynamics in patients with hypertension undergoing pneumonectomy

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400092643

Enrollment

Unknown

Registered

2024-11-20

Start date

2025-02-01

Completion date

Unknown

Last updated

2024-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension

Interventions

Lung recruitment maneuver combined with individualized positive end-expiratory pressure strategy (individualized group):Lung recruitment maneuver combined with individualized positive end-expiratory p

R:Routine protective ventilation

Eligibility

Sex/Gender

All

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1.age >=18 years; 2.preoperative hypertension grade 1-3; 3.ASA grade 1-3 4.expected duration of OLV >60 minutes

Exclusion criteria

Exclusion criteria: 1. Pregnancy or breastfeeding; 2.acute respiratory distress syndrome; 3.heart failure; 4.intracranial hypertension; 5.mechanical ventilation within the past 15 days; 6.pneumothorax or pulmonary bullae; 7.Chronic obstructive pulmonary disease (COPD) requiring oxygen or continuous positive airway pressure; 8.Previous pneumonectomy; 9.participating in another interventional study with similar primary outcome;

Design outcomes

Primary

Measure	Time frame
Mean arterial pressure ;Heart rate;	—

Secondary

Measure	Time frame
The amount of fluids used;The amount of intraoperative rescue drugs;	—

Countries

China

Contacts

Public ContactJiru Zhang

Affiliated Hospital of Jiangnan University

zjr2010508@163.com+86 15852512299

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026