Gestational diabetes mellitus
Conditions
Interventions
GDM group:personalized diet and exercise intervention
Control group:N/A
Sponsors
Jiangsu Province Hospital (The First Affiliated Hospital with Nanjing Medical University)
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1.Age between 18 and 40 years; 2.Pre-pregnancy BMI between 18.5 kg/m^2 and 28 kg/m^2; 3.Ability to read, understand, and sign the informed consent form; 4.The pregnant woman receives prenatal care and delivers at the study hospital.
Exclusion criteria
Exclusion criteria: 1.Twin or multiple pregnancies; 2.Pre-existing diabetes mellitus (PGDM), including gestational diabetes diagnosed during pregnancy (fasting blood glucose >=7.0 mmol/L or OGTT 2-hour blood glucose >= 11.1 mmol/L); 3.Poorly controlled pre-existing chronic hypertension (blood pressure >= 140/90 mmHg); 4.Coexisting severe liver or kidney disease (alanine aminotransferase greater than 2.5 times the upper limit of normal, creatinine greater than 132 mmol/L); 5.Current or recent use of medications affecting glucose metabolism, including steroids, hydroxyprogesterone caproate, antiretroviral drugs, etc.; 6.Mental disorders and severe psychological conditions (measured using scales: PHQ-9 for depression and GAD-7 for anxiety); 7.Coexisting severe infections; 8.Inability to adequately understand the requirements of the project, poor compliance, refusal to use continuous glucose monitoring (CGM) or to perform self-monitored blood glucose (SMBG) tests as required.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Adverse Pregnancy Outcomes Occurrence;Long-Term Incidence of Type 2 Diabetes Mellitus;Long-Term Incidence of Cardiovascular Disease (CVD); | — |
Countries
China
Contacts
Public ContactYun Liu
Jiangsu Provincial People's Hospital (The First Affiliated Hospital of Nanjing Medical University)
Outcome results
None listed