To investigate the effects of regional anesthesia and perioperative blood glucose management on postoperative myocardial injury in elderly patients undergoing hip fracture surgery

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400092621

Enrollment

Unknown

Registered

2024-11-20

Start date

2025-01-01

Completion date

Unknown

Last updated

2024-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

myocardial injury

Interventions

General anesthesia intubation group (GA group) :None

Combined nerve block group (NB group) :Hip nerve block anesthesia was added

Part 1: Divided into MINS group and non MINS group based on different MINS outcomes.:None

Eligibility

Sex/Gender

All

Age

65 Years to No maximum

Inclusion criteria

Inclusion criteria: Part One: 1. ASA grades I to IV; 2. Age 65 or above; 3. Low-energy damage; 4. Concurrent surgical treatment of single hip fractures (femoral neck fractures, intertrochanteric fractures, subtrochanteric fractures); 5. First hip operation; 6. Patients without multiple fractures; 7. Patients with no pathological fractures caused by osteoarthritis or tumor metastasis; 8. Patients with complete follow-up data such as basic information and medical history information; 9. Troponin measurements should be conducted at least once before and 3 days after surgery. Part Two: 1. Age 65 years or older; 2. Low-energy damage; 3. Concurrent surgical treatment of single hip fractures (femoral neck fractures, intertrochanteric fractures, subtrochanteric fractures); 4. ASA grades I to III; 5. At least one troponin measurement before surgery and one troponin measurement within 3 days after surgery.

Exclusion criteria

Exclusion criteria: Part Two: 1. Patients with pathological fractures due to tumor metastasis; 2. Patients with periprosthetic fractures; 3. Patients with multiple fractures; 4. Puncture site infection; 5. Lower extremity nerve injury; 6. Patients not suitable for general anesthesia; 7. Contraindications for local anesthesia; 8. Coagulation dysfunction; 9. Elevated cTn caused by stroke, pulmonary vascular embolism, pulmonary hypertension, renal insufficiency and other non-cardiac factors; 10. Patients unable to cooperate with investigators.

Design outcomes

Primary

Measure	Time frame
Incidence of MINS in elderly patients undergoing surgery for hip fracture;	—

Secondary

Measure	Time frame
Postoperative survival in hospital and at 30 days;Postoperative complication;ICU and total length of stay;Blood glucose level;Postoperative mortality (30 days, 1 year, 3 years);	—

Countries

China

Contacts

Public ContactChen Zheng

Shanghai Sixth People's Hospital

15000027620@163.com+86 189 3017 0175

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026