Skin barrier function as a predictor of the severity of radiation skin injury

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2400092617

Enrollment

Unknown

Registered

2024-11-20

Start date

2024-10-30

Completion date

Unknown

Last updated

2024-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Radiation skin injury

Interventions

Case series :N/A

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1) RTOG , CTCAE standard grading of 0 to 4; 2)18 years <= age; 3) Those who signed the informed consent form

Exclusion criteria

Exclusion criteria: 1) age >70 years; 2) oral corticosteroid therapy; 3) history of radiotherapy at the same site; 4) patients with connective tissue diseases (e.g., scleroderma and lupus erythematosus); 5) termination of treatment for various reasons; 6) psychiatric psychiatric disorders

Design outcomes

Primary

Measure	Time frame
black pigment of skin;skin haemoglobin;skin moisture;transdermal water loss;skin elasticity;skin oil;skin pH;Skin Symptom Scores;	—

Secondary

Measure	Time frame
RTOG toxicity scores;CTCAE scores;	—

Countries

China

Contacts

Public ContactZhou Yong

Department of Dermatology, the 1th Medical Center of PLA General Hospital, Beijing

Zhouyong301pfk@163.com+86 138 0137 8765

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026