Bladder tumor
Conditions
Interventions
Experimental group:cTURBT, artery intubation chemotherapy and intravesical chemotherapy instillation
Control group:Radical resection of the bladder
Sponsors
The first affiliated hospital of soochow university
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. MIBC, T2a-T2b, N0, M0 disease. 2. NMIBC, T1G3 which is multiple, recurrent, and >=3cm diameter. (multiple is defined as two or more locations) 3. NMIBC, BCG-relapsing or BCG-unresponsive. 4. NMIBC, T1G3 with CIS at bladder or prostatic urethra. 5. Age >=18, male or female. 6. ECOG score 0-1. 7. Patients are able to comply with research and follow-up procedures. 8. Patients have the ability to understand and voluntarily sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Previous occurrence or concurrent presence of other malignant tumors. 2. Existence of serious or uncontrollable systemic diseases. 3. A female patient who plans a pregnancy or breast-feeding. 4. Hearing loss >Level 2. 5. Heart failure NYHA grading >Grade III. 6. Peripheral neuropathy >Grade 2. 7. There is a serious or uncontrollable systemic disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| OS(Overall Survival);DFS(Disease-free Survival);PFS(Progression Free Survival); | — |
Secondary
| Measure | Time frame |
|---|---|
| DSS(Disease-specific Survival);Success rate of bladder preservation;Salvage radical resection rate;QOL(Quality Of Life); | — |
Countries
China
Contacts
Public ContactYuhua Huang
The first affiliated hospital of soochow university
Outcome results
None listed