Cardioembolic stroke
Conditions
Interventions
Exposed Group:None
Control Group:None
Sponsors
The Sixth Medical Center of PLA General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1) Age >= 18 years; 2) The diagnosis of atrial fibrillation was based on the patient's admission electrocardiogram, 24-hour ambulatory electrocardiogram, and reference to the ESC2020 atrial fibrillation guideline diagnostic criteria; 3) CHA2DS2-VASc score:male >= 2 score, female >= 3 score(C:Congestive heart failure,H: Hypertension, A: Age >= 75 years, D: Diabetes mellitus, S: Stroke, V: Vascular disease, A: Age 65-74 years, Sc: Sex category (female)); 4) Contraindications to oral anticoagulant therapy or HAS-BLED score >=3 score(Hypertension, Abnormal renal/liver function, Stroke, Bleeding history or predisposition, Labile INR, Elderly (>65 years), Drugs/alcohol concomitantly; 1 point each ); 5) Patients after percutaneous left atrial appendage closure; 6) Patients volunteered for CT imaging follow-up.
Exclusion criteria
Exclusion criteria: 1) Device implantation >= 2; 2) Subjects had a life expectancy of less than 2 years; 3) Patients with complications during LAAC; 4) Patients who are participating in other interventional clinical trials; 5) Those who refused to participate or were clearly unable to complete the follow-up visit at the established time point.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The composite endpoint of stroke, systemic embolism, transient ischemic attack, cardiovascular death, death of unknown cause, and all-cause mortality within 24 months after discharge.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Peri-device leak;Device-related thrombus;Bleeding Events;Device Shoulder Protrusion; | — |
Countries
China
Contacts
Public ContactChen Tao
The Sixth Medical Center of PLA General Hospital
Outcome results
None listed