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The study on the effectiveness and safety of liposomal bupivacaine for ilioinguinal nerve block in elderly patients after PFNA surgery

The study on the effectiveness and safety of liposomal bupivacaine for ilioinguinal nerve block in elderly patients after PFNA surgery

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400092576
Enrollment
Unknown
Registered
2024-11-19
Start date
2024-11-28
Completion date
Unknown
Last updated
2024-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pain management

Interventions

Control group:A comprehensive evaluation should be carried out at the preoperative visit of anesthesia, and the samples of patients who are not suitable for this study protocol should be excluded: pat
Patients with anatomical variations or local infections at the puncture site and contraindications to neuraxial anesthesia
Those with preoperative basic cognitive function MMSE score < 24 points
Those who are not planned to be admitted to the intensive care unit after surgery. The coagulation function should be fully evaluated before the combined spinal-epidural anesthesia in the control gro
experimental group:The samples of patients who are not suitable for this study protocol will be excluded: those with severe medical systemic diseases and liver and kidney insufficiency
Those who are not planned to be admitted to the intensive care unit after surgery. All patients should be adequately assessed for coagulation function prior to the procedure, using ultrasound to loca

Sponsors

Sanming Second Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 100 Years

Inclusion criteria

Inclusion criteria: Patients aged =65 years with diagnosed femoral fractures who have undergone closed reduction and internal fixation; signed informed consent to participate in this study.

Exclusion criteria

Exclusion criteria: Severely obese patients, those allergic to bupivacaine or liposomal components; those with severe cardiopulmonary insufficiency, liver and kidney dysfunction and other systemic diseases; those with mental illness or cognitive impairment unable to cooperate with the study, and those with a history of chronic opioid use.

Design outcomes

Primary

MeasureTime frame
Perioperative pain score;

Secondary

MeasureTime frame
Mental state score;Postoperative complication rate;Stress indicators assessment (blood glucose, hemodynamic changes);Postoperative joint function recovery situation;Rescue analgesia rate;Patient satisfaction;Hospitalization time;Duration of analgesia;

Countries

China

Contacts

Public ContactTang Shuting

Regular staff members

812298316@qq.com+86 158 0603 7655

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026