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The Effects of iPACK Block Combined with Adductor Canal Block and Local Infiltration on Movement-Evoked Pain Following Total Knee Arthroplasty: A Randomized Controlled Trial

The Effects of iPACK Block Combined with Adductor Canal Block and Local Infiltration on Movement-Evoked Pain Following Total Knee Arthroplasty: A Randomized Controlled Trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400092564
Enrollment
Unknown
Registered
2024-11-19
Start date
2024-11-30
Completion date
Unknown
Last updated
2024-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Total Knee Arthroplasty

Interventions

control group:Adductor canal block + local infiltration
experimental group:adductor canal block + iPACK block + local infiltration

Sponsors

Honghui Hospital, Xi’an Jiaotong University, Xi’an
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Adult patients scheduled to undergo TKA under general anesthesia; (2) ASA classification of I-III; (3) Patients voluntarily participating in the study and signing an informed consent form

Exclusion criteria

Exclusion criteria: (1) Age 80 years; (2) Body mass index >40 kg/m2; (3) Knee varus-valgus deformity =30°; (4) Knee flexion deformity =30°; (5) Patients with contraindications to peripheral nerve block; (6) History of chronic pain or opioid use; (7) Lower limb neuropathy or neurological impairment; (8) Allergy or intolerance to any component of the regimen; (9) Mental illness that affects cognition, judgment and compliance.

Design outcomes

Primary

MeasureTime frame
Exercise-Induced F-VAS Pain Score at 8 Hours Postoperatively;

Secondary

MeasureTime frame
Postoperative rest and exercise-induced pain;24h postoperative opioid consumption;Time to first analgesia;Number of pains;Postoperative 24h TUG test;Postoperative QoR-15 scale score;Postoperative sleep quality score;Length of hospitalization;

Countries

China

Contacts

Public ContactKai Wang

Department of Anesthesiology, Honghui Hospital, Xi’an Jiaotong University, Xi’an

wang8352854@163.com+86 153 8352 8584

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026