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Effect of midazolam on postoperative delirium in elderly patients undergoing spinal surgery

Effect of midazolam on postoperative delirium in elderly patients undergoing spinal surgery: a prospective, double-blind, randomized controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400092537
Enrollment
Unknown
Registered
2024-11-19
Start date
2024-11-20
Completion date
Unknown
Last updated
2024-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative delirium

Interventions

Experimental group:Intravenous induction of midazolam was performed at 0.02mg/kg
Control group:The same dose of saline was administered intravenously

Sponsors

Department of Anesthesiology, Ningbo Sixth Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to No maximum

Inclusion criteria

Inclusion criteria: 1) Age =65 years old; 2) Spinal surgery with general anesthesia is planned; 3) American Society of Anesthesiologists Medical Conditions (ASA) Class I-III; 4) Agreed to participate in the study and have signed the informed consent. Patients were enrolled in the study if they met all the inclusion criteria

Exclusion criteria

Exclusion criteria: 1) American Society of Anesthesiologists (ASA) Level V and above; 2) Patients admitted to ICU before surgery, and/or transferred to ICU after surgery due to medical conditions; 3) Multi-site fracture surgery 4) Untreated or undertreated hyperthyroidism 5) Patients with severe cardiovascular disease (such as heart attack, unstable angina and congestive heart failure within six months) 6) Patients with increased eye pressure (such as glaucoma) 7) Patients who are unable to communicate normally or have serious mental illness 8) Patients with increased intracranial pressure 9) Patients with moderate to severe dementia were evaluated by MMSE before surgery 10) Refusing to sign the study informed consent

Design outcomes

Primary

MeasureTime frame
Incidence of delirium;Incidence of agitation;

Secondary

MeasureTime frame
Visual Analogue Scale, VAS;

Countries

China

Contacts

Public ContactZhu Miao

Ningbo Sixth Hospital

zhumiao002@163.com+86 189 6984 2670

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026