Congenital heart disease
Conditions
Interventions
Sodium oxybutyrate group:Sodium oxybutyrate
Propofol group:Propofol
Sponsors
Beijing Children's Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
No minimum to 6 Years
Inclusion criteria
Inclusion criteria: (1) Children aged 0-6 years who were diagnosed with simple ventricular septal defect or atrial septal defect and scheduled to undergo repair under cardiopulmonary bypass were included; (2) The legal guardian of the child signs the informed consent.
Exclusion criteria
Exclusion criteria: (1) Patients with preoperative malignant tumors; (2) Patients with active rheumatic system disease before surgery and not yet under control; (3) Patients with serious and uncontrolled infection before surgery; (4) Patients with significant respiratory function impairment before surgery; (5) Patients with severe pre-operative anticoagulant dysfunction; (6) Patients with severe renal failure and/or liver failure before surgery; (7) Patients who underwent Extracorporeal Membrane Oxygenation (ECMO) before or after surgery; (8) Patients who used aortic balloon reperfusion before or after surgery; (9) Patients with preoperative massive cerebral infarction or cerebral hemorrhage.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Acute kidney injury; | — |
Secondary
| Measure | Time frame |
|---|---|
| Acute liver injury;Myocardial injury;Cyclic fluctuation;General indicators: postoperative extubation time, length of stay in the ICU, total length of stay, and related complications during hospitalization; | — |
Countries
China
Contacts
Public ContactWang Fang
Beijing Children's Hospital, Capital Medical University
Outcome results
None listed