Burst suppression
Conditions
Interventions
Short-term VM group:Valsalva maneuver
Control group:No operation is performed
Long-term VM group:Valsalva maneuver
Sponsors
The 2nd Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1.Patients undergoing HIFU ablation for liver tumor; 2.General anesthesia is required during the operation; 3.American Society of Anesthesiologists (ASA) Physical condition grades I - III; 4.Participate voluntarily and be able to understand and sign informed consent; 5.Patients aged 18-85 years;
Exclusion criteria
Exclusion criteria: 1.Patients with stroke, cerebral hemorrhage, immune system disorders or neurological disorders; 2.Patients with preoperative MMSE = 23; 3.Patients taking drugs that affect the central nervous system; 4.Patients with preoperative pneumothorax, pulmonary bullosa, and underlying respiratory diseases; 5.Patients who are expected to have difficulty managing the airway; 6.Acute coronary syndrome, sinus bradycardia (heart rate 28 kg/m2); 8.Patients with stage 4 or 5 chronic kidney disease; 9.Patients who are expected to require mechanical ventilation after surgery; 10.Hearing, intellectual, communication, cognitive disabilities; 11.For any reason, they could not be included in the study or the researchers considered it inappropriate to include the study; 12.Patients who are expected to be transferred to the ICU after surgery;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| EEG data (PSD, ApEn, SaEn, PeEn, CFC);Burst suppression; | — |
Secondary
| Measure | Time frame |
|---|---|
| Emergence agitation;Delirium;Postoperative recovery quality;Intraoperative vital signs (SpO2, heart rate, blood pressure); | — |
Countries
China
Contacts
Public ContactShiyu Shu
The 2nd Affiliated Hospital of Chongqing Medical University
Outcome results
None listed