Recurrent Pregnancy Loss
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: URPL Patients 1. Experienced two or more consecutive spontaneous miscarriages with the same partner. 2. Age: 18–45 years. 3. Patients who agree to participate in this study and sign the informed consent. 4. Capable of being followed up until the end of the pregnancy. Subjects with No History of Miscarriage 1. Age: 18–40 years. 2. Patients who agree to participate in this study and sign the informed consent. 3. Capable of being followed up until the end of the pregnancy.
Exclusion criteria
Exclusion criteria: URPL Patients 1. History of live birth. 2. Miscarriage or stillbirth occurring after 12 weeks of pregnancy. 3. Non-consecutive miscarriages. 4. Known genetic, endocrine, coagulation, immune, anatomical, or infectious causes identified through screening. 5. Difficulty in follow-up or other conditions deemed unsuitable for participation by the researchers. Participants with No History of Miscarriage 1. History of spontaneous miscarriage. 2. History of ectopic pregnancy. 3. History of missed miscarriage or stillbirth. 4. Known genetic, endocrine, coagulation, immune, anatomical, or infectious causes identified through screening. 5. Inability or unwillingness to complete the study requirements or to cooperate with follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Live Birth Rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Preterm Birth Rate;Pregnancy Loss Rate;Incidence of obstetric complications;Adverse Fetal Outcomes;Maternal and infant endings; | — |
Countries
China
Contacts
Shanghai Jiao Tong University School of Medicine, Renji Hospital