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Comparative study on sedation effect of remazolam and midazolam in patients undergoing intrathecal anesthesia

Comparative study on sedation effect of remazolam and midazolam in patients undergoing intrathecal anesthesia

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400092466
Enrollment
Unknown
Registered
2024-11-18
Start date
2024-11-20
Completion date
Unknown
Last updated
2024-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fear and anxiety about invasive procedures

Interventions

M Group:midazolam was used for sedation before anesthesia
R Group:Remazolam was used for sedation before anesthesia

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Patients who are scheduled to undergo transanal or transsacrococcygeal surgery (anoplasty, mixed hemorrhoidal stripping and internal ligation, sacrococcygeal cyst resection, etc.); 2.Patients undergoing ultrasound-guided spinal anesthesia during anesthesia preparation room; 3.Patients and their families sign informed consent forms;

Exclusion criteria

Exclusion criteria: 1.The patient and his family refuse; 2.Severe hepatic and renal insufficiency, severe respiratory and circulatory system diseases; 3.Obvious abnormality of coagulation function, disease of coagulation system, recent use of anticoagulant drugs; 4.Allergic to local anesthetics and the test drugs; 5.Skin infection at the puncture site and other cachexia; 6.Patients with myasthenia gravis, schizophrenia, and severe depressive states; 7.Sleep apnea hypopnea syndrome patients;

Design outcomes

Primary

MeasureTime frame
Wake up time;

Secondary

MeasureTime frame
Duration of sedation onset ;Adverse reactions;

Countries

China

Contacts

Public ContactXiaoqiang Li

West China Hospital, Sichuan University

39006900@qq.com+86 18980601475

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026