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Effect of humidified high flow nasal catheter oxygen inhalation on postoperative atelectasis in patients with esophageal cancer: a randomized controlled trial

Effect of humidified high flow nasal catheter oxygen inhalation on postoperative atelectasis in patients with esophageal cancer: a randomized controlled trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400092457
Enrollment
Unknown
Registered
2024-11-18
Start date
2024-11-18
Completion date
Unknown
Last updated
2024-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

esophageal cancer

Interventions

Experimental group:High flow nasal catheter oxygen therapy
Control group:Nasal catheter oxygen inhalation

Sponsors

Affiliated Cancer Hospital of Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1) Patients who signed informed consent and were willing to complete the study according to the protocol; 2) Patients scheduled for elective esophageal cancer surgery with one lung ventilation; 3) ASA grade I~III; 4) The age ranged from 18 to 80 years.

Exclusion criteria

Exclusion criteria: 1) Severe asthma or COPD, pulmonary bullae, pneumothorax, emphysema, bronchopleural fistula, etc; 2) Facial, nasal or airway anatomical abnormalities, nasal diseases; 3) Any pulmonary disease, including bronchopulmonary dysplasia, respiratory distress syndrome, active upper respiratory tract infection, asthma, tracheal or subglottic stenosis; 4) Before operation, the oxygen of finger pulse was lower than 95%. 5) High risk patients with reflux aspiration;

Design outcomes

Primary

MeasureTime frame
Pulmonary ultrasound score;

Secondary

MeasureTime frame
PaO2/FiO2;Incidence of hypoxia events (SpO2 = 90%);Intraoperative hemodynamics;Sedation Scale (RASS) score;Pulmonary complications;

Countries

China

Contacts

Public ContactJun Zhang

Affiliated Cancer Hospital of Fudan University

snapzhang@aliyun.om+86 21 6404 1990

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026