Carcinoma of esophagus
Conditions
Interventions
control group:Preoperative ultrasound-guided T9-10 epidural catheterization was performed, 2 % lidocaine 3 ml was injected, the block plane was measured, and the catheter position was confirmed. One h
Experimental group:Preoperative ultrasound-guided T9-10 epidural catheterization was performed, 2 % lidocaine 3ml was injected, the block plane was measured, and the catheter position was confirmed. O
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Age = 18 years; 2. AASA grade I-III; 3. Elective minimally invasive oesophagectomy (including minimally invasive three-incision, minimally invasive two-incision, mediastinoscopy combined with laparoscopy, robot-assisted minimally invasive oesophagectomy); 4. Subjects clearly understand and voluntarily participate in this study, can sign the informed consent and voluntarily comply with the study process.
Exclusion criteria
Exclusion criteria: 1. the existence of epidural contraindications: such as severe spinal or thoracic deformities, coagulation disorders, local infections, the patient's refusal or inability to cooperate; 2. the existence of contraindications to the use of morphine, local anaesthetics; 3. Patients with language communication disorders; 4. Previous history of anaesthetic drug abuse; 5. Severe respiratory disease, sleep apnea syndrome, severe hepatic and renal insufficiency, severe cardiovascular and cerebrovascular disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of hypotension within 24 hours after operation.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Degree of decrease in minimum blood pressure from baseline blood pressure within 24 hours after surgery;Incidence of more than 20% decrease in minimum blood pressure from baseline blood pressure within 24 hours after surgery;Incidence of mean arterial pressure <65 mmHg within 24 hours after surgery;Incidence of moderate to severe pain on postoperative days 1, 2 and 3;Incidence of supplemental analgesia on postoperative days 1, 2 and 3;Incidence of pulmonary complications during hospitalisation;Incidence of anastomotic leak;Mortality rate in hospital; | — |
Countries
China
Contacts
Public ContactFei Liu
West China Hospital of Sichuan University
Outcome results
None listed