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Study on Clinical and Molecular Mechanisms of In-Stent Restenosis (ISR)

Study on Clinical and Molecular Mechanisms of In-Stent Restenosis (ISR)

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400092419
Enrollment
Unknown
Registered
2024-11-15
Start date
2024-12-01
Completion date
Unknown
Last updated
2024-11-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Heart Disease

Interventions

Experimental group:PCSK9 inhibitors combined with standard drug therapy

Sponsors

the First Affiliated Hospital of Guangxi Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. At least 18 years old; 2. CAG shows significant narrowing in at least one coronary artery + treatment with drug-eluting stent implantation.

Exclusion criteria

Exclusion criteria: 1.Used anti-inflammatory medications for six months prior to the implantation of the stent, accompanied by inflammatory diseases such as severe infections and autoimmune diseases. 2. Implanted with a metal bare stent or a biodegradable stent. 3. Unable to tolerate oral antiplatelet medications, did not regularly take antiplatelet drugs post-surgery, or has a special medication history. 4. Diseases causing immune dysfunction or other serious systemic diseases.

Design outcomes

Primary

MeasureTime frame
Target Lesion Failure;

Secondary

MeasureTime frame
Quality of Life Rating;Safety and tolerability;

Countries

China

Contacts

Public ContactYubo Xie

Department of Anesthesiology, the First Affiliated Hospital of Guangxi Medical University

aban829@163.com+86 77105671

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026