chronic rhino sinusitis with nasal polyps
Conditions
Interventions
Control group:Conventional medicine + blank USW diathermy therapy (machine will not on)
USW group:Conventional medicine + USW diathermy therapy (machine will on)
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria 1) Subjects diagnosed with CRSwNP; 2) >=18 years old; 3) CRS with bilateral NP; 4) Endoscopic bilateral nasal polyp score of at least 1 (out of 8) for each nasal cavity; 5) Symptoms lasting at least 8 weeks prior to study entry, including: moderate or severe symptoms (2 or 3 points), nasal congestion, or nasal congestion, and a weekly mean severity score of at least 1 point (range 0 to 3 points) at randomization; 6) At least one other symptom, such as partial loss of smell (hyposmia), complete loss of smell (anosmia), or anterior or posterior rhinorrhea; 7) Patients with concomitant asthma must have been stable with conventional asthma treatment for the previous 6 weeks.
Exclusion criteria
Exclusion criteria: Exclusion criteria 1) Previous USW treatment; 2) Had sinus surgery (including removal of nasal polyps) within 6 months prior to visit; 3) Patients with forced expiratory volume in the first second (FEV1)<=50% of the expected normal value (co-asthmatic patients); 4) Postnasal sinus polyps were present; 5) Acute sinusitis; 6)Upper respiratory tract infection; 7) Cystic fibrosis; 8) Mycotic rhinosinusitis; 9) Yang Syndrome; 10) Kartagener syndrome or ciliary immotility syndrome.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Nasal polyp score under bilateral nasal endoscopy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Nasal congestion or obstruction score;SNOT-22 total score;Smell test (UPSIT) score;Loss-of-smell score;Lund-Mackay CT total score;Rhino sinusitis disease severity;Baseline peak nasal inspiratory flow;Baseline blood eosinophils; | — |
Countries
China
Contacts
Public ContactHe Chengqi
West China Hospital, Sichuan University
Outcome results
None listed