polycystic ovary syndrome
Conditions
Interventions
Treatment Group:Acupuncture and moxibustion+Letrozole
Control Group:Placebo needle+Letrozole
Sponsors
Fujian Maternity and Child Health Hospital College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1.Conform to the diagnostic criteria of western medicine and traditional Chinese medicine; 2.The age is between 20 and 40; 3.Sign the informed consent form voluntarily.
Exclusion criteria
Exclusion criteria: 1. Exclude patients with hyperandrogenism caused by other reasons, such as Cushing syndrome, late-onset congenital adrenal hyperplasia, androgen-secreting ovarian and adrenal tumors, etc., and other diseases that cause ovulation dysfunction, such as pituitary or hypothalamic amenorrhea, hyperprolactinemia, premature ovarian failure, etc.; 2. Exclude organic diseases or other endocrine diseases; 3. Patients with severe liver and kidney, cardiovascular and cerebrovascular diseases, hematopoietic system dysfunction and mental illness; 4. Patients who have taken hormones and anticoagulant drugs in the past 3 months, or who have participated in other clinical experiments; 5. Those under the age of 20 or over the age of 40; 6. Those who do not meet the inclusion criteria or have incomplete information that affects the judgment; 7. Those who cannot adhere to the course of treatment, withdraw halfway or lose follow-up; 8. Those who have serious complications in the test.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pregnancy rate;Ovulation rate;Early miscarriage rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| TCM symptom score;Glycolipid metabolism;Endocrine metabolism;Histone acetylation modification;Mitochondrial oxidative stress;Akt/mTOR/Fox0 signaling pathway; | — |
Countries
China
Contacts
Public ContactXu Jinbang
Fujian Maternity and Child Health Hospital College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University
Outcome results
None listed