tumor chemotherapy-induced gastrointestinal reactions
Conditions
Interventions
Experimental group:Conventional antiemetic therapy+ Yiwei formula
Control group:Conventional antiemetic therapy+Jianpi Yiwei Formula placebo (1/10 Jianpi Yiwei Formula)
Sponsors
Cancer Hospital, Chinese Academy of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Patients who have not previously undergone chemotherapy; (2) Aged between 18 and 80 years; (3) Diagnosed with non-small cell lung cancer via pathological examination; (4) Individuals of all genders intending to receive two or more cycles of carboplatin-based chemotherapy (administered every 21 or 28 days); (5) Karnofsky Performance Status (KPS) score of 70 or above.
Exclusion criteria
Exclusion criteria: (1) Presence of unstable brain metastases; (2) Planned to receive or have received epigastric or cranial radiotherapy within the past four weeks; (3) History of major gastrointestinal surgery (such as cholecystectomy, significant intestinal resection, or gastrectomy) within the last five years; (4) A documented history of chronic gastrointestinal diseases (including ulcerative colitis and Crohn's disease) assessed for potential impact; (5) Evidence of gastrointestinal bleeding; (6) A history of substance abuse, including drugs or alcohol; (7) Any relevant circumstances that may compromise the evaluation of the study; (8) Known allergies to any components in the Jianpi Yiwei prescription.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Complete Control rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| The impact of nausea and vomiting on daily life;Control rate to anorexia;The impact of fatigue on daily life;Stool situation;Control rate to bloating; | — |
Countries
China
Contacts
Public ContactLi Feng
Cancer Hospital, Chinese Academy of Medical Sciences
Outcome results
None listed