infertility
Conditions
Interventions
Group 1:From the day of gonadotropin initiation, ovarian stimulation was performed using recombinant FSH in combination with LH preparations (including recombinant LH or human menopausal gonadotropin)
Group 2:From the day of gonadotropin initiation, ovarian stimulation was performed using recombinant FSH
Sponsors
The First Affiliated Hospital of Nanjing Medical University (Jiangsu Province People's Hospital)
Eligibility
Sex/Gender
Female
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: (1) Patients aged 45 years or younger, scheduled to undergo their first or second IVF/ICSI cycle with GnRH agonist long protocol; (2) Ovarian endometriotic cysts confirmed by radiological examination with a maximum diameter =1.2ng/ml or AFC>=5; (4) BMI<=30kg/m².
Exclusion criteria
Exclusion criteria: (1) History of >=2 failed IVF/ICSI attempts, recurrent spontaneous abortion (RSA), or repeated implantation failure (RIF); (2) Presence of moderate to severe hydrosalpinx, or conditions preventing fresh embryo transfer such as endometrial polyps; (3) Couples with chromosomal numerical/structural abnormalities or monogenic disorders requiring preimplantation genetic testing (PGT).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Metabolomics;Serum LHestradiol and progesterone Level ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Assisted Reproductive Technology (ART) Outcomes;Ongoing pregnancy rate;Follicular Output Rate;Follicle-To-Oocyte Index;fertilization rate;implantation rate;Biochemical pregnancy rate;Clinical pregnancy rate;Live birth rate;Number of oocytes retrieved;number of MII oocytes;Number of transferrable embryos;Number of high-quality embryos;Number of fresh embryo transfers;Endometrial thickness on embryo transfer day;pregnancy loss;ectopic pregnancy;pregnancy complications; | — |
Countries
China
Contacts
Public ContactDiao Feiyang
The First Affiliated Hospital of Nanjing Medical University (Jiangsu Provincial People's Hospital)
Outcome results
None listed