Colorectal cancer
Conditions
Interventions
Colorectal cancer :None
patient
Health, Benign disease patient group:None
Sponsors
Zhujiang Hospital, Southern Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. No history of previous tumors; 2.Age between 18 and 75 years; 3. Male or non-pregnant, non-lactating female; 4.No prior radiotherapy or chemotherapy before enrollment; 5.Able to provide sufficient and qualified blood samples; 6.Voluntary signature of informed consent. For the Colorectal Cancer Group: 7.Preoperative colonoscopy pathology diagnosis of colorectal adenocarcinoma or high-grade adenoma. For the Control Group: 8.Some with certain gastrointestinal symptoms, with a recommendation for colonoscopy; colonoscopy pathology diagnosis of benign gastrointestinal diseases; 9.Some healthy individuals with no significant findings in colonoscopy pathology; 10.Other confirmed tumors unrelated to colorectal cancer, including gastric cancer, liver cancer, esophageal cancer, biliary cancer, pancreatic cancer, as well as common non-digestive system tumors such as lung cancer, breast cancer, cervical cancer, and thyroid cancer.
Exclusion criteria
Exclusion criteria: 1.Plasma contamination in the laboratory; 2.Participation in another clinical trial within 30 days before enrollment; 3.Pregnant or lactating women; 4.History of tumors and corresponding tumor treatments; 5.Blood transfusion within 30 days before blood collection; 6.History of organ, bone marrow, or stem cell transplantation; 7.Health conditions unsuitable for blood collection; 8.Incomplete clinical data (including TNM staging, tumor volume, pathological classification, site of occurrence, vascular invasion, age, sex, depth of invasion, degree of differentiation, alcohol history, smoking history, etc.); 9.Other conditions deemed unsuitable for the study by the researchers
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Methylation level; | — |
Countries
China
Contacts
Public ContactCui Chunhui
Zhujiang Hospital, Southern Medical University
Outcome results
None listed