Obesity
Conditions
Sponsors
Shanghai Sixth People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: (1) BMI >= 28 kg/m^2 and < 35 kg/m^2; (2) Aged 18 to 60 years, inclusive; (3) The subject or the subject's family agrees and signs an informed consent form, being able to cooperate with various examinations during the clinical research period.
Exclusion criteria
Exclusion criteria: (1) History of head trauma or epilepsy, or a family history of epileptic seizures; (2) Presence of implanted metal devices, pacemakers, claustrophobia, or any other contraindications to functional magnetic resonance imaging (fMRI); (3) Existence of diabetes mellitus or unstable cardiovascular diseases; (4) Greater than 5% change in body weight within the past 3 months; (5) Receipt of weight loss treatment within the past 6 months; (6) Diagnosis of psychiatric disorders or current use of psychotropic medications; (7) Abnormal findings on brain magnetic resonance imaging (MRI); (8) Severe hepatic or renal dysfunction; (9) Inability to communicate with researchers or staff, or participation in other clinical studies simultaneously.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the reaction time of Go/no-go task; | — |
Secondary
| Measure | Time frame |
|---|---|
| fNIRs(functional near - infrared spectroscopy);electroencephalography;functional magnetic resonance imaging (fMRI);Food Craving Questionnaire-Trait(FCQ-T);Food Craving Questionnaire-State(FCQ-S);stroop task test score;Weight;Body mass index;visual analogue scale; | — |
Countries
China
Contacts
Public ContactZheng Yuanyi
Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
Outcome results
None listed