Respiratory depression, Hypotension
Conditions
Interventions
Cyclophenol group:Anesthesia with cyclosporine as the main component
Combination therapy of remifentanil besylate and etomidate:During painless gastroscopy anesthesia, the combination of remifentanil besylate and etomidate was administered with remifentanil besylate an
Sponsors
People's Hospital Of Deyang City
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients undergoing elective painless gastroscopy and colonoscopy examinations; 2.Age range of 18 to 65 years old (including 18 and 65 years old), gender is not limited; 3.Body Mass Index (BMI): 18.5-28 kg/m^2; 4. American Society of Anesthesiologists (ASA) classification: I-II; 5.The subjects voluntarily participated in the study and signed the informed consent form for this study.
Exclusion criteria
Exclusion criteria: 1.Individuals with a history of allergies to opioid drugs, benzodiazepines, etomidate, Cyclophenol, propofol, flumazenil, or naloxone excipients; 2. Expected operation time exceeds 45 minutes; 3.Use beta blockers, anti anxiety drugs, and antidepressants; 4.Suspected of abusing narcotic analgesics or sedatives, as well as alcoholics; 5.Electrocardiogram prompt: heart rate100 beats/min or severe arrhythmia; 6.History of acute respiratory infection within 2 weeks without cure; 7.Individuals with a history of severe heart, brain, lung, liver, kidney, or metabolic diseases, as well as those with neurological and muscular disorders (such as myasthenia gravis) or mental illnesses; 8. Preoperative hypertension patients with systolic blood pressure>180 mmHg and/or diastolic blood pressure>110 mmHg, or hypotension patients<90/60 mmHg; 9.Individuals with a history of gastrointestinal diversion; 10. Individuals with a history of abnormal surgical anesthesia recovery in the past; 11. Predicting the possibility or occurrence of difficult airways, such as modified Mahalanobis grading III-IV; 12. Pregnant or lactating women and patients with fertility plans within 3 months (including males); 13.Other researchers believe that other subjects who are not suitable to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of respiratory depression; | — |
Countries
China
Contacts
Public ContactJing Sui
People's Hospital Of Deyang City
Outcome results
None listed