medication-related osteonecrosis of the jaws
Conditions
Interventions
Patients who were clinically diagnosed with MRONJ (Mandibular resection due to mandibular osteonecrosis):None
Control group (perform enlarged mandibular resection due to tongue cancer and buccal cancer
perform orthognathic surgery to remove bone due to malocclusion):None
Sponsors
Zhejiang University School of Medicine Stomatology Hospital
Eligibility
Sex/Gender
All
Age
20 Years to 90 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: All the following standards must be met before they can be included in the test: ? Patients diagnosed with bisphosphonate osteonecrosis of jaw in our hospital; ? Patients diagnosed with tongue cancer and buccal cancer in our hospital who need to undergo extended mandibular resection; ? Patients who need orthognathic surgery in our hospital; ? Participate in this clinical trial voluntarily, abide by the requirements of this clinical trial and sign the informed consent form.
Exclusion criteria
Exclusion criteria: The investigator determines that participation in this clinical trial is not appropriate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| expression level of marker of H-type vessels; | — |
Countries
China
Contacts
Public ContactZhijian Xie
Zhejiang University School of Medicine Stomatology Hospital
Outcome results
None listed