post-EST bleeding
Conditions
Interventions
experimental group:Hemostatic powder
control group:Hemostatic Clip
Sponsors
Beijing Friendship Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Aged between 18 and 80 years old (2) Patients undergoing ERCP for malignant biliary obstruction, cholangitis, or choledocholithiasis and who are likely to have exudative bleeding after the proposed intraoperative EST dissection
Exclusion criteria
Exclusion criteria: (1) Subjects who do not personally consent to participate in this clinical trial (2) Patients with arterial bleeding after EST incision (3) Patients with coagulation disorders or thrombocytopenia, presence of platelets 1.5x normal value or INR >2.5 (4) patients with organ dysfunction (5) Patients who are unable to discontinue antiplatelets or anticoagulants (except acetylsalicylic acid) (6) Patients with confirmed pregnancy or breastfeeding (7) Allergic reactions to study materials (8) Suspected active preoperative gastrointestinal bleeding (9) Difficulty in accessing Vater's potbelly endoscopically (10) Patients enrolled in other clinical trials within four weeks
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hemostatic success in immediate post-EST exudative bleeding; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of delayed bleeding after successful hemostasis of the first exudative hemorrhage;Overall treatment failure rate;Further intervention methods;Incidence of adverse events;Duration of hemostasis;Duration of operation ; | — |
Countries
China
Contacts
Public ContactPeng Li
Beijing Friendship Hospital, Capital Medical University
Outcome results
None listed