Sleep disorders
Conditions
Interventions
the ozonated autohemotherapy group(the O3-AHT group):ozonated autohemotherapy
control group:autologous blood donation
Sponsors
Zhujiang Hospital of Southern Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1.Age: 18-45 ; gender: female; 2.Able to take care of themselves in their daily lives, with an Activity of Daily Living (ADL) score >60; 3.Able to understand, read and write Chinese normally, with a score of >=27 on Mini-mental State Examination(MMSE); 4.No clinical manifestations of perimenopausal syndrome; 5.Laparoscopic surgery under general anaesthesia with elective tracheal intubation; 6.American Society of Anaesthesiologists (ASA) I-III; 7.It was anticipated that intraoperative bleeding would exceed 150ml and that acute isovolumic haemodilution would not be required, provided there were no contraindications. The patient's general physical condition was deemed to be satisfactory, with a haemoglobin concentration of at least 110g/L (haematocrit of 0.33). Furthermore, the technique could be employed in instances where surgery was necessary to reduce blood viscosity and enhance microcirculation. 8.insomnia: Pittsburgh sleep quality index (PSQI) score >7 and Insomnia Severity Index (ISI) >=15.
Exclusion criteria
Exclusion criteria: 1.Chronic use of sedatives, antidepressants, drug or alcohol dependence, acute alcoholism; 2.Fava bean disease: glucose-6-phosphate dehydrogenase deficiency; 3.Toxic diffuse goitre (Graves' disease); 4.Patients with haemochromatosis, copper or iron therapy; 5.pregnancies; 6.Anticoagulant (sodium citrate) allergy;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pittsburgh sleep quality index, PSQI; | — |
Secondary
| Measure | Time frame |
|---|---|
| Insomnia Severity Index;sleep quality numerical rating scale;visual analogue scale; | — |
Countries
China
Contacts
Public ContactQian Qian
Zhujiang Hospital of Southern Medical University
Outcome results
None listed