chronic hepatitis B
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) All patients in the case group met the diagnostic criteria for CHB in the Guidelines for the Prevention and Treatment of Chronic Hepatitis B (2015 Updated edition) formulated by the Chinese Society of Hepatology and the Chinese Society of Infectious Diseases; 2) All subjects in the control group were excluded from hepatitis B infection by clinical examination; 3) All patients received treatment in the same hospital, with complete clinical data and age > 18 years old.
Exclusion criteria
Exclusion criteria: 1) Patients with malignant tumors, cardiovascular and cerebrovascular accidents, endocrine system diseases, autoimmune diseases, blood system diseases, other acute and chronic systemic infections except hepatitis B infection; 2) Patients with severe trauma, surgery, or transfusion and transfusion of blood components within 1 month before enrollment; 3) Except for patients with liver fibrosis caused by HBV infection; 4) Pregnant or lactating patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| systemic immune-inflammation index, SII; | — |
Secondary
| Measure | Time frame |
|---|---|
| platelet-to-lymphocyte ratio, PLR;neutrophil-to-lymphocyte ratio, NLR;lymphocyte-to-monocyte ratio, LMR;monocyte-to-lymphocyte ratio, MLR; | — |
Countries
China
Contacts
Hangzhou Linping Hospital of Integrated Traditional Chinese and Western Medicine