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The ED50 of sufentanil when combined with midazolam for pain-free bronchoscopy

The ED50 of sufentanil when combined with midazolam for pain-free bronchoscopy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400092251
Enrollment
Unknown
Registered
2024-11-13
Start date
2024-11-14
Completion date
Unknown
Last updated
2024-11-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory disease

Interventions

Group A youth group (18-44 years old):During induction of anesthesia, subjects in group A given 2mg midazolam intravenously.
group B middle-aged group (45-59 years old):During induction of anesthesia, subjects in group B given 2mg midazolam intravenously
Group C Young and old (60~74 years old):During induction of anesthesia, subjects in group C was given 1mg midazolam intravenously.
group D elderly group (75-89 years old):During induction of anesthesia, subjects in group D was not given midazolam intravenously.

Sponsors

Yan'an Hospital of Kunming City
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 89 Years

Inclusion criteria

Inclusion criteria: The patients who underwent painless fiberoptic bronchoscopy were of all genders and aged 18-89 years, with ASA grades I to III.

Exclusion criteria

Exclusion criteria: The patients examined were of all genders and aged 18-89 years old, with ASA grades I to III. Exclusion criteria: Patients with a history of severe hepatic and renal insufficiency, respiratory failure and cardiac insufficiency; Patients with bradycardia or sick sinus syndrome at rest before operation; Failure to maintain blood oxygen during examination and examination; Abuse or long-term use of narcotic, sedative, or analgesic drugs, and have a history of mental illness; Check for more than 30 minutes or unable to communicate.

Design outcomes

Primary

MeasureTime frame
The sufentanil dose;

Secondary

MeasureTime frame
Heart rate, mean arterial pressure, pulse oxygen saturation and end expiratory carbon dioxide pressure were measured at each time point;Time of examination, time to wake up, adverse reactions;The degree of coughing reaction;

Countries

China

Contacts

Public ContactYang Maiqiao

Yan'an Hospital of Kunming City

1690726990@qq.com+86 138 8871 7397

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026