malignant obstructive jaundice
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1). Age between 18 and 70 years; (2). Presence of symptoms of obstructive jaundice (such as jaundice of the skin, jaundice of the sclera, and dark yellow urine), with serum total bilirubin > 200 µmol/L upon hospital admission; (3).Preoperative imaging and clinical diagnosis suggest distal malignant biliary obstruction; (4).Underwent preoperative biliary drainage at the participating hospital of this study; (5). Underwent curative surgical treatment at the participating hospital of this study; (6). Informed consent obtained from the patient and their family, with voluntary participation in the study.
Exclusion criteria
Exclusion criteria: (1). Patients with surgical contraindications or those unable to undergo curative surgery for any reason; (2).Patients who only receive palliative surgical treatment; (3). Postoperative pathological diagnosis indicating benign disease; (4).Incomplete medical records; (5).Presence of diabetes, metabolic syndrome, or other severe chronic systemic diseases; (6).Prior to inclusion, patients who have undergone procedures such as biliary imaging, biliary surgery, bile duct or gallbladder puncture and drainage, biliary stent placement, or nasobiliary drainage.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bile acid metabolomics; | — |
Secondary
| Measure | Time frame |
|---|---|
| General situation;Intraoperative situation;Pathological data; | — |
Countries
China
Contacts
General Hospital of Western Theater Command