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A study on the correlation between immunosuppressive therapy and prognosis in patients with IgA nephropathy after complete remission of urine protein: a single-center, two-way cohort study

A study on the correlation between immunosuppressive therapy and prognosis in patients with IgA nephropathy after complete remission of urine protein: a single-center, two-way cohort study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400092201
Enrollment
Unknown
Registered
2024-11-12
Start date
2024-11-15
Completion date
Unknown
Last updated
2024-11-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

IgA nephropathy

Interventions

Immunosuppressive therapy group:NA

Sponsors

Affiliated Hospital of Guangdong Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1.From January 1, 2013 to December 31, 2025, patients who were 18 years old or older in the Department of Nephrology of the Affiliated Hospital of Guangdong Medical University, confirmed to have IgA nephropathy by renal biopsy, and the clinical and pathological data were kept intact, and the urine protein was completely relieved for at least 3 months after immunosuppressive therapy, and the follow-up was = for 3 years.

Exclusion criteria

Exclusion criteria: 1. Systemic diseases that may lead to secondary renal IgA deposition, such as chronic hepatitis virus infection, human immunodeficiency virus (HIV) infection, autoimmune diseases including systemic lupus erythematosus (SLE), allergic purpura nephritis (HSPN), Sjögren's syndrome (SS), ankylosing spondylitis (AS), etc. 2.(2) Patients with crescent nephritis (>50% of patients with pathological diagnosis), minimal change nephropathy with IgA deposition and other types of glomerular diseases; 3.(2) Transplanted kidney or combined with other pathological types, such as minimal lesions, membranous nephropathy, diabetic nephropathy, etc. 4.?(3) There are comorbidities that affect treatment, such as malignant tumors, pregnancy, severe malnutrition, etc. 5.(4) Severe infection, serious gastrointestinal complications or other reasons that make it impossible to receive oral medication; 6.(5) Patients with IgA nephropathy in stage 5 CKD.

Design outcomes

Primary

MeasureTime frame
Urinary protein recurrence rate within 3 years;

Secondary

MeasureTime frame
Renal combined endpoint events;

Countries

China

Contacts

Public ContactLuo Mianna

Affiliated Hospital of Guangdong Medical University

luomianna@126.com+86 759 2387414

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026