ventilator-associated pneumonia(VAP)
Conditions
Interventions
Experimental group:The PH value of the drainage above the tracheotomy sac was determined. Jejunal tube insertion was given when the PH value was less than 6, and botox injection was given when the PH
normal group:Basic care was also present in the intervention group, including: head elevation 30-45 degrees
Continuous enteral nutrient pumping
Oral care with chlorine-containing disinfectant
The intracapsular pressure of tracheotomy was maintained at 25-30cmH2O. The drainage above the tracheotomy sac is attracted every 4-6 hours
Patients with sedation wake up daily
Daily ventilator evacuation experiment.
Sponsors
Beijing Rehabilitation Hospital Affiliated to Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: If the patient has had an artificial airway for more than 48 hours, is over 18 years old, needs EN support and informed consent from the family, and the balloon pressure is monitored after admission, the balloon pressure is maintained at 25-30cmH2O, and the drainage fluid from the balloon is extracted with a syringe every 4-6 hours. If the patient's saliva is more than 3 ml at a time or the patient's saliva is seen flowing out through the mouth, Can be randomly assigned to the experimental group and the control group.
Exclusion criteria
Exclusion criteria: 1. Persistent pneumonia or pulmonary infiltration confirmed by chest radiography upon admission; 2. Low immune function 3. Active gastrointestinal bleeding or acute gastrointestinal perforation; 4. Severe esophageal varices; Cerebrospinal fluid rhinorrhea or transnasal surgery; 5. The throat or esophagus is narrow or obstructed, and cannot be inserted into the gastroscope or nasogastric tube; 6. Allergic to polyvinyl chloride nasal feeding tube; 7. Has undergone any major abdominal surgery (i.e. oesophageal, stomach, duodenal or pancreatic surgery) or any abdominal surgery in the past month; 8. Severe heart or lung insufficiency (i.e. severe hypertension, severe arrhythmia, active myocardial infarction, severe heart failure, severe asthma, severe respiratory failure, making it difficult to breathe while lying flat; 9. Jejunostomy or gastrostomy; 10.30 days after participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ventilator-associated pneumonia; | — |
Countries
China
Contacts
Public ContactYanyanYin
Beijing Rehabilitation Hospital Affiliated to Capital Medical University
Outcome results
None listed