Laryngeal cancer
Conditions
Interventions
Control group:General anesthesia induction (intravenous injection of midazolam 0.05mg/kg, sufentanil 0.3 µ g/kg, propofol 2mg/kg, cisatracurium 0.15mg/kg), anesthesia maintenance (intravenous infusion
Esmolol group:On the basis of the control group, anesthesia induction increased esmolol by 0.5mg/kg, anesthesia maintenance increased esmolol by 30 µ g/kg/min, and stopped pumping until the end of the
Sponsors
Tengzhou Central People's Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patients with laryngeal cancer undergoing partial laryngectomy under general anesthesia, aged 40-80 years, ASA I-II grade, signed an informed consent form before surgery.
Exclusion criteria
Exclusion criteria: Exclude patients with cardiovascular, respiratory, neurological, and psychiatric disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood pressure and heart rate values;Interleukin-1ß;Blood glucose level;Interleukin-6;Interleukin-8;TNF-a;Blood cortisol level; | — |
Secondary
| Measure | Time frame |
|---|---|
| Patients' total anesthesia dosage;Incidence of adverse reactions in patients;Intraoperative bleeding volume of patients;Postoperative recovery time of patients; | — |
Countries
China
Contacts
Public ContactZhang Mingyang
Tengzhou Central People's Hospital
Outcome results
None listed