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To evaluate the value of tumor organoid drug sensitivity in guiding the prognosis of platinum-resistant recurrent ovarian epithelial carcinoma

To evaluate the value of tumor organoid drug sensitivity in guiding the prognosis of platinum-resistant recurrent ovarian epithelial carcinoma

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400092121
Enrollment
Unknown
Registered
2024-11-11
Start date
2024-06-15
Completion date
Unknown
Last updated
2024-11-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ovarian cancer

Interventions

Sponsors

West China Second Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 18-75 years old; 2. Patients with epithelial ovarian cancer confirmed by histopathology and/or cytology; 3. Patients who progress in platinum-containing chemotherapy or relapse = 3 months; 7. The patients voluntarily joined the study and signed the informed consent form (ICF), with good compliance and follow-up.

Exclusion criteria

Exclusion criteria: 1.Patients who have had other malignant tumors within 5 years, except skin cancer that has been cured; 2.Patients who have had clinically significant (i.e., active) heart disease (e.g., congestive heart failure, symptomatic coronary artery disease, arrhythmia, etc.) or myocardial infarction in the past 12 months; 3.Patients with a history of psychotropic drug abuse and unable to quit or patients with mental disorders; 4. Patients deemed unsuitable for inclusion by the investigators.

Design outcomes

Primary

MeasureTime frame
Objective response rate;

Secondary

MeasureTime frame
Progression free survival;Overall survival;

Countries

China

Contacts

Public ContactYin Rutie; Li Qingli

West China Second Hospital of Sichuan University

deviljackaot@sina.com+86 181 8060 9015

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026