endometriosis
Conditions
Interventions
Pregnancy complicated with endometriosis group:None
Pregnancy complicated with other ovarian tumor group:None
Perimenopausal pelvic endometriosis with surgical treatment group:None
Perimenopausal pelvic endometriosis with follow up group:None
Sponsors
Obstetrics and Gynaecology Hospital of Fudan University
Eligibility
Sex/Gender
Female
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: Endometriosis during pregnancy: ? Experimental Group:Patients in early pregnancy (6-8 weeks of gestation) with clinical or imaging diagnosis (B-ultrasound and/or MRI) of endometriosis (including but not limited to OMA);? control group: Pregnant women with ovarian tumors diagnosed clinically or by imaging (B-ultrasound and/or MRI) Endometriosis during perimenopause: 40-55 years old, in perimenopause; 2. Clinical diagnosis or imaging diagnosis (B-ultrasound and/or MRI) of pelvic endometriosis (OMA or DE ± adenomyosis)
Exclusion criteria
Exclusion criteria: Endometriosis during pregnancy: ?experimental group: Suspected or confirmed malignant tumors before pregnancy; Choosing abortion for personal reasons during pregnancy; Those with contraindications to MRI examination; Pathological pregnancy (ectopic pregnancy, missed abortion, hydatidiform mole, etc.) ?control group: Ovarian endometrioid cyst suspected by imaging; No imaging report of ovarian tumor follow-up during pregnancy; No surgery and no pathological report during pregnancy to 1 year after delivery Endometriosis during perimenopause:1. History of previous malignant tumor; 2. History of previous LHBSO or bilateral oophorectomy; 3. Contraindications to MRI examination; 4. Postoperative pathology suggests only adenomyosis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The accuracy of imaging diagnosis of endometriosis (the consistency between MRI/ultrasound and pathological results);The rate of malignant transformation of pelvic endometriosis during perimenopause; | — |
Secondary
| Measure | Time frame |
|---|---|
| Endometriosis progression rate during pregnancy;pregnancy outcome;The incidence of maternal complications during pregnancy;The incidence of decidualization in endometriosis during pregnancy; | — |
Countries
China
Contacts
Public ContactYi Xiaofang
Obstetrics and Gynaecology Hospital of Fudan University
Outcome results
None listed