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Development and evaluation of a ctDNA content estimation method

Development and evaluation of a ctDNA content estimation method

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400092108
Enrollment
Unknown
Registered
2024-11-11
Start date
2024-11-11
Completion date
Unknown
Last updated
2024-11-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

16 cancers, including Lung cancer, breast cancer, colorectal cancer, liver cancer, esophageal cancer, stomach cancer, pancreatic cancer, ovarian cancer, cervical cancer, nasopharyngeal cancer, endometrial cancer, gallbladder cancer, lymphoma, prostate cancer, bladder cancer and kidney cancer.

Interventions

Lung cancer:NA
Esophageal cancer:NA
Stomach cancer:NA
Cervical cancer:NA
Endometrial cancer:NA
Gallbladder cancer:NA
Prostate cancer:NA
Kidney cancer:NA
Ovarian cancer:NA
Nasopharyngeal cancer:NA
Lymphoma:NA
Bladder cancer:NA

Sponsors

Fudan University Shanghai Cancer Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 74 Years

Inclusion criteria

Inclusion criteria: 1: Pathologically diagnosed as any one of 16 types of cancer, including Lung cancer, breast cancer, colorectal cancer, liver cancer, esophageal cancer, stomach cancer, pancreatic cancer, ovarian cancer, cervical cancer, nasopharyngeal cancer, endometrial cancer, gallbladder cancer, lymphoma, prostate cancer, bladder cancer and kidney cancer. 2: Age eligible for the study: 40=age<75 3: Did not received any systemic or local anti-tumor treatment before screening, including but not limited to surgical resection, radiotherapy and chemotherapy, endocrine therapy, targeted therapy, immunotherapy, cell therapy, interventional therapy, etc. 4: Able to sign informed consent, and be willing to comply with sample collection, assessment and follow up of this study.

Exclusion criteria

Exclusion criteria: 1: Female patients who are pregnant, lactating; 2: Patients with a known malignancy or history of malignancy; 3: Severe acute infection (e.g. severe or critical COVID-19, sepsis, etc.) or febrile illness (body temperature of = 38.5 °C) within 14 days prior to screening; 4: Taken any of the following medications within 14 days before screening: Intravenous or oral use of glucocorticoids, azacitidine, decitabine, procainamine, hydrazine Hydrazine, arsenic trioxide; 5: Received organ transplant, bone marrow transplant, stem cell transplant before screening, or received blood transfusion within 30 days prior to screening; 6: Other situations not suitable for enrollment determined by investigator.

Design outcomes

Primary

MeasureTime frame
Limit of Detection;Accuracy;

Countries

China

Contacts

Public ContactYu Xianjun

Fudan University Shanghai Cancer Center

yuxianjun@fudanpci.org+86 189 1726 6285

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026