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Research on Establishing Optimal Prognostic Profile of Oral Cancer "Tumor-Fluid" Based on Mitochondrial Fusion/Division Dynamic Balance Coupled Metabolic Reprograms

Research on Establishing Optimal Prognostic Profile of Oral Cancer "Tumor-Fluid" Based on Mitochondrial Fusion/Division Dynamic Balance Coupled Metabolic Reprograms

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400092103
Enrollment
Unknown
Registered
2024-11-11
Start date
2024-11-15
Completion date
Unknown
Last updated
2024-11-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral squamous cell carcinoma

Interventions

Observation group:None

Sponsors

Bejing Stomatological Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: (1) Age: = 18 years old. (2) Gender: Unrestricted. (3) Location of lesions: tongue, cheek mucosa, upper and lower gums, floor of mouth, hard palate mucosa. (4) Primary patients with squamous cell carcinoma confirmed by preoperative pathological biopsy, with preoperative clinical staging of cT1-4N0-3M0 (AJCC 8th edition). (5) General condition: Through routine examinations such as the three major tests, blood biochemistry tests, electrocardiograms, etc., surgical contraindications are ruled out, and distant metastases are excluded through chest X-rays and/or abdominal B-ultrasound and/or enhanced CT and/or MRI and/or PET/CT examinations.

Exclusion criteria

Exclusion criteria: (1) Complete clinical and baseline data related to comorbidities cannot be obtained. (2) Patients who have undergone surgery or radiation therapy for the purpose of radical cure before admission to our hospital. (3) Pregnant or lactating women. (4) Individuals with mental, intellectual disabilities, and cognitive difficulties.

Design outcomes

Primary

MeasureTime frame
Levels of mitochondrial protein;Overall survival, OS;Disease-free survival, DFS;

Countries

China

Contacts

Public ContactZhien Feng

Bejing Stomatological Hospital, Capital Medical University

jyfzhen@126.com+86 186 0134 9511

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026