lumbar spondylolisthesis Lumbar disc herniation Lumbar vertebral fracture
Conditions
Interventions
Bupivacaine liposome group (LB group):Received bupivacaine liposomes for TLIP block after surgery
Rawpivacaine group (Group R):Received rawpivacaine for TLIP block after surger
Sponsors
The First Affiliated Hospital of Anhui University of Science and Technology (Huainan First People's Hospital)
Eligibility
Sex/Gender
All
Age
20 Years to 64 Years
Inclusion criteria
Inclusion criteria: Age: 20 to 64 years. Physical fitness index (BMI):18.5-28 kg/m2. Patients proposed to undergo elective lumbar surgery, including lumbar discectomy, lumbar fusion, etc. American Association of Anesthesiologists (ASA) grades I-III. There was no preoperative history of severe neuropathic pain. Signed the informed consent form and was willing to undergo the follow-up visit.
Exclusion criteria
Exclusion criteria: Allergic or contraindication to local anesthetic drugs (including bupivacaine, ropivacaine and its derivatives). The coagulation time and platelet number were abnormal. Infection at the puncture site. There are severe cardiovascular, respiratory, liver and kidney dysfunction. Long-term administration of opioids before surgery. Pregnant or lactating women. Mental illness or cognitive impairment, can not cooperate with the researcher to complete the questionnaire survey.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| QoR-40(Quality of Recovery-40); | — |
Secondary
| Measure | Time frame |
|---|---|
| NRS scores at 6,12,24,48,72 hours;Time of the first compression of the postoperative analgesic pump;Number of additional remedial analgesia required 72 hours after surgery;OBAS(Overall Benefit of Analgesia Score); | — |
Countries
China
Contacts
Public ContactYuanyuan Zhao
The First Affiliated Hospital of Anhui University of Science and Technology (Huainan First People's Hospital)
Outcome results
None listed