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Identification of biomarkers and pathogenesis for early colorectal cancer based on plasma metabolomics and machine learning

Identification of biomarkers and pathogenesis for early colorectal cancer based on plasma metabolomics and machine learning

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400092091
Enrollment
Unknown
Registered
2024-11-08
Start date
2024-03-01
Completion date
Unknown
Last updated
2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

early colorectal cancer

Interventions

Sponsors

Peking University First Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Colorectal cancer group and colorectal adenoma 1. Colonoscopy at the Endoscopy Center of Peking University First Hospital; 2. Complete clinical data; 3. Sign the informed consent form; 4. Age >=18 and = 18 and<= 80 years old 5. No known malignant tumors other than colorectal

Exclusion criteria

Exclusion criteria: Colorectal cancer group and colorectal adenoma Exclusion Criteria (one of the following): 1. Age 80 years old; 2. Known concurrent or previous malignant tumors at other sites other than colorectal cancer; 3. Have undergone endoscopic, surgical or chemoradiotherapy treatment; 4. Do not agree to participate in the study or have incomplete clinical data; 5. Combined with metabolic diseases or hematologic diseases; 6. Combined with underlying diseases such as cardiovascular and cerebrovascular, liver, kidney, etc.; 7. Lactating or pregnant women; 8. Significant stress response within 2 weeks of blood collection; 9. Any symptoms of acute illness within 2 weeks of blood collection; 10. Have taken special drugs (antibiotics, hormones, non-steroidal anti-inflammatory drugs, etc.) within 2 weeks of blood collection Healthy control group 1. Age 80 years old; 2. Known concurrent or previous malignant tumors at other sites other than colorectal cancer; 3. Have undergone endoscopic, surgical or chemoradiotherapy treatment; 4. Do not agree to participate in the study or have incomplete clinical data; 5. Combined with metabolic diseases or hematologic diseases; 6. Combined with underlying diseases such as cardiovascular and cerebrovascular, liver, kidney, etc.; 7. Lactating or pregnant women 8. Significant stress response within 2 weeks of blood collection; 9. Any symptoms of acute illness within 2 weeks of blood collection; 10. Have taken special drugs (antibiotics, hormones, non-steroidal anti-inflammatory drugs, etc.) within 2 weeks of blood collection

Design outcomes

Primary

MeasureTime frame
Pathological findings;Information on endoscopy;

Secondary

MeasureTime frame
general data;

Countries

China

Contacts

Public ContactFeng Wang

Peking University First Hospital

bjmuwangfeng@126.com+86 10 83572437

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026