Disorders of consciousness
Conditions
Interventions
Group A: Conventional treatment group:none
Group B: tDCS group:Transcranial direct current stimulation (tDCS)
Group C: MNS combined with tDCS group:Median nerve electrical stimulation (MNS) combined with transcranial direct current stimulation (tDCS)
Sponsors
The Third Affiliated Hospital of Sun Yat sen University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1Age = 18 years old; 2 Consciousness disorders caused by trauma, stroke, or hypoxia; 3 The course of the disease is = 2 weeks; 4 Diagnosed as vegetative state (VS/UWS) or MCS based on clinical diagnostic criteria and CRS-R; 5 Stable vital signs and no progressive neurological symptoms; 6 If using consciousness improvement drugs for at least 2 weeks or more, no dose adjustment will be made during the enrollment period; 7 Voluntarily participate and sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1Previous history of brain tumor, traumatic brain injury, epilepsy (or EEG indicating epileptic like changes), or mental disorders History; 2 Consciousness disorders present before stroke; 3 Skull defect, intracranial hypertension, intracranial infection; 4 Metal or electronic device implants (such as pacemakers, cochlear implants, deep brain stimulators, dynamic,Pulse tumor clip, internal fixation device after entriculoperitoneal shunt surgery, etc); 5 Unstable heart disease, high blood pressure; 6 Other serious diseases that may affect the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Coma Recovery Scale - Revised Score;Awakening rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Glass Coma Scale Score;Glasgow Outcome Score;Resting electroencephalogram;Event related potential; | — |
Countries
China
Contacts
Public ContactXiquan Hu
The Third Affiliated Hospital of Sun Yat sen University
Outcome results
None listed