Partial hepatectomy
Conditions
Interventions
H Group: H: hydromorphone 10mg
HN Group:HN: hydromorphone 10mg+ Nalbuphine 50mg
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1) Patients who are expected to treated with controlled intravenous analgesia after elective laparoscopic partial hepatectomy; 2) ASAI-III level; 3) Age 18 or older, regardless of gender. 4) No communication barriers, able to understand the study process and the use of pain scales, and able to operate self-controlled analgesia equipment; 5) Voluntarily participated and signed the informed consent.
Exclusion criteria
Exclusion criteria: 1) Participants who have participated in other drug clinical trials within the last 3 months; 2) Those who have taken monoamine oxidase inhibitors or antidepressants within 15 days; Psychiatric disorders (schizophrenia, mania, bipolar disorder, psychosis, etc.), and a history of long-term use of psychotropic drugs 3) Patients with chronic pain who have research related drug allergies, long-term use of opioids, or drug addiction; 4) Patients with a history of severe digestive disorders (known or suspected gastrointestinal obstruction, including paralytic ileus), severe respiratory depression, and asthma 5) Patients who cannot express their wishes correctly; Poor compliance, unable to complete the experiment according to the study protocol; 6) Patients transferred to ICU after surgery; 7) Pregnant or lactating women; 8) Researchers consider it inappropriate to participate in this experiment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Nausea and vomiting; | — |
Secondary
| Measure | Time frame |
|---|---|
| NRS pain score; | — |
Countries
China
Contacts
Public ContactLIUFEI
West China Hospital of Sichuan University
Outcome results
None listed