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Correlation of Pulse Perfusion Index Changes with Subsequent Analgesic Efficacy in Low Concentration Labor Epidural Analgesia: A Prospective Observational Single-center Study

The effect of pulse perfusion index changes in epidural labor analgesia

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400092071
Enrollment
Unknown
Registered
2024-11-08
Start date
2024-12-01
Completion date
Unknown
Last updated
2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Labor pain

Interventions

Patients were grouped according to the difference in PPI recorded at each time point after epidural labor analgesia was administered:None

Sponsors

Women and Children's Hospital, Xiamen University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1)Full-term nulliparous women who scheduled to receive LEA; 2)American Society of Anesthesiologists (ASA) class I-II.

Exclusion criteria

Exclusion criteria: 1)History of severe circulatory and respiratory disease; 2)Body mass index (BMI) >30kg/m2; 3)Gestational diabetes mellitus; 4)Gestational hypertension; 5)Thyroid system diseases; 6)Cervical dilatation >5cm at the time of labor analgesia; 7)History of peripheral vascular disease; 8)Contraindications to epidural analgesia in labor; 9)Accidentally dural puncture; 10)Analgesia failure (bilateral inadequate block extent; unilateral block); 11)Inability to accurately report Visual Analog Scale (VAS) scores; 12)Recent use of medication that may interfere with the results of the PPI (nifedipine).

Design outcomes

Primary

MeasureTime frame
Pulse perfusion index (PPI);

Secondary

MeasureTime frame
Epidural drug use during labor analgesia;Basic clinical characteristics of maternity;Basic information about the fetus;Pain scores;Adverse events during labor;

Countries

China

Contacts

Public ContactFei Shuai

Women and Children's Hospital, Xiamen University

feishuaid@hotmail.com+86 163 9592 9844

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026