Chronic kidney disease
Conditions
Interventions
CKD group and normal renal function group:None
Sponsors
Zhongshan Hospital of Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: The inclusion criteria for this study consist of two groups of participants: the CKD group and the normal renal function group. Participants in the CKD group must be adults aged 18 to 80 years who have been diagnosed with chronic kidney disease (GFR < 60 mL/min/1.73 m², persisting for more than 3 months, or with proteinuria/hematuria). They should have no history of acute kidney injury, renal replacement therapy, or kidney transplantation, and must be able to understand and comply with the study requirements, completing all follow-up visits and examinations. Participants in the normal renal function group must be adults aged 18 years or older with normal kidney function, undergoing contrast-enhanced ultrasound for non-kidney-related conditions (such as gallbladder or thyroid disease). They should also be able to understand and comply with the study requirements, completing all follow-up visits and examinations.
Exclusion criteria
Exclusion criteria: The exclusion criteria specify that the CKD group will exclude patients with severe dysfunction of other organs, recent acute kidney injury, medications affecting kidney function, active infections, a history of chronic infectious diseases or malignancy, as well as those with severe cognitive impairment, psychiatric disorders, current or recent participation in other clinical trials, allergy to UMI contrast agents, or pregnant/breastfeeding women. For the normal renal function group, individuals with abnormal kidney function or a history of kidney disease, those using medications that affect kidney function, those with severe cardiovascular disease or liver failure, pregnant/breastfeeding women, or individuals allergic to ultrasound contrast agents will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| microvessel density;microvessel curvature; | — |
Countries
China
Contacts
Public ContactHong Han
Zhongshan Hospital of Fudan University
Outcome results
None listed