Diquat poisoning
Conditions
Interventions
Sponsors
First Affiliated Hospital, Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Age
12 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) patients who were poisoned by oral administration of diquat and were seen within 72 hours of poisoning; (2) patients whose blood and urine samples from poisoned patients were clearly present after mass spectrometry tests; (3) age greater than or equal to 12 years; (4) diagnosis of psychiatric disorders made by a specialist.
Exclusion criteria
Exclusion criteria: (1) patients who were not orally poisoned; (2) patients who had combined ingestion of other lethal doses of poisons, such as paraquat; (3) patients who suffered from sepsis, cardiac failure, severe hepatic or renal disease, malignant tumors, and other terminal illnesses or other life-threatening conditions prior to the onset of acute intoxication; and (4) patients who suffered from epilepsy, uncontrolled autoimmune encephalitis, central nervous system infection, patients suffering from cerebral hemorrhage, cerebral infarction, or severe closed craniocerebral injury resulting in impaired neurological function within 3 months; (5) patients with mid- to late-stage pregnancies; (6) patients younger than 12 years of age; and (7) patients with poorly documented medical history data.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 28-day survival rate;Serum diquat concentration;Incidence of encephalopathy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Alanine aminotransferase;Serum creatinine;WBC count;APACHE-II score; | — |
Countries
China
Contacts
Public ContactYuanqiang Lu
First Affiliated Hospital, Zhejiang University School of Medicine
Outcome results
None listed