tuberculosis infertility
Conditions
Interventions
LTBI positive group:NA
LTBI negative group:NA
Sponsors
Reproductive Hospital Affiliated to Shandong University
Eligibility
Sex/Gender
Female
Age
21 Years to 40 Years
Inclusion criteria
Inclusion criteria: Couples aged 21-40 years old, the first IVF / ICSI cycle, normal / rare menstruation and infertility time more than 2 years of women, the woman anti-Mullerian hormone ( AMH ) = 1.2ng / ml.
Exclusion criteria
Exclusion criteria: 1.Couples receiving egg donation ; 2.PGT-M or PGT-SR should be performed in women and / or men with chromosomal abnormalities or / and genetic diseases. 3.Uterine malformations ( uterine septum, unicornuate uterus, bicornuate uterus ), adenomyosis, submucosal fibroids, etc. ; 4. Women with a history of preeclampsia, diagnosed diabetes, chronic hypertension or chronic kidney disease, malignant tumor, long-term use of corticosteroids / immunosuppressive agents, history of tuberculosis or treatment history. High-risk groups of tuberculosis : HIV-infected patients and AIDS patients, diabetic patients, patients with rheumatic immune disease treated with glucocorticoids, immunosuppressive agents, biological agents, radiotherapy and chemotherapy, patients with malignant tumors, dialysis and solid organ or bone marrow transplant patients with inflammatory bowel disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of latent tuberculosis infection in infertility population;The incidence of active tuberculosis in patients with latent tuberculosis infection during pregnancy;live birth rate;Incidence of complications during pregnancy / puerperium;neonatal outcomes; | — |
Secondary
| Measure | Time frame |
|---|---|
| abortion ratio;high quality embryo rate; | — |
Countries
China
Contacts
Public ContactYe Zheng
State Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive Health, Shandong University
Outcome results
None listed