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ED50 of ciprofol in inhibiting gastroscope insertion response in patients of different genders when combined with oxycodone

ED50 of ciprofol in inhibiting gastroscope insertion response in patients of different genders when combined with oxycodone

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400092030
Enrollment
Unknown
Registered
2024-11-07
Start date
2024-06-03
Completion date
Unknown
Last updated
2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gastric disease

Interventions

Female group:Slowly inject 0.05mg/kg of oxycodone intravenously, and after 2 minutes, inject ciprofol according to Dixon's modified sequential method. The initial dose is 0.4mg/kg, and the ratio of ad
If a negative reaction occurs, the next patient will receive a lower dose of ciprofol. The experiment ends when there are 7 turning points between negative and positive results.
male group:Slowly inject 0.05mg/kg of oxycodone intravenously, and after 2 minutes, inject ciprofol according to Dixon's modified sequential method. The initial dose is 0.4mg/kg, and the ratio of adja

Sponsors

Xuanwu Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to 59 Years

Inclusion criteria

Inclusion criteria: 1.Patients undergoing elective outpatient painless gastroscopy examination; 2.ASA ?~?; 45~59 years old; 3.BMI 18.5~27.9;

Exclusion criteria

Exclusion criteria: 1.Predictable difficult airway; 2.Be allergic to soybean, eggs, opiates, or ciprofol; 3.History of drug abuse and mental illness; 4.Researchers believe that subjects who are not suitable for selection;

Design outcomes

Primary

MeasureTime frame
reaction during gastroscope insertion;

Countries

China

Contacts

Public ContactTianLong Wang

Xuanwu Hospital, Capital Medical University

w_tl5595@hotmail.com+86 10 83199333

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026