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Effect of remazolam besylate on hemodynamic stability and quality of recovery in elderly patients undergoing ultrasound bronchoscopic mediastinal lymph node biopsy

Effect of remazolam besylate on hemodynamic stability and quality of recovery in elderly patients undergoing ultrasound bronchoscopic mediastinal lymph node biopsy

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400092023
Enrollment
Unknown
Registered
2024-11-07
Start date
2024-11-13
Completion date
Unknown
Last updated
2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory disease

Interventions

Propofol group (p group, n=30) :Anesthesia induction: Group P (propofol 1.5 mg/kg), Sufentanil 0.3 µg/kg, vecuronium 0.1 mg/kg.
Remazolam benzoate group (R group, n=30):Anesthesia induction: R (Remazolam 0.2 mg/kg), Sufentanil 0.3 µg/kg, vecuronium 0.1 mg/kg.

Sponsors

Yan'an Hospital of Kunming City
Lead Sponsor

Eligibility

Sex/Gender
All
Age
70 Years to 99 Years

Inclusion criteria

Inclusion criteria: Mediastinal lymph node biopsy with ultrasound bronchoscopy under general anesthesia laryngeal mask was performed in elderly patients, aged =70 years, regardless of gender, BMI 18-25 kg/m2, ASA grade I to III.

Exclusion criteria

Exclusion criteria: ? Patients who are allergic to the drugs used in this study; (2) There were coagulation disease and cardiopulmonary function intolerance before operation; ? Patients with mental illness or cognitive impairment; ?BMI>30 kg/m²; (5) Serious organoplasmic degeneration of heart, brain, kidney and other organs; ? History of drug use or addictive drugs;

Design outcomes

Primary

MeasureTime frame
Quality of awakening;

Secondary

MeasureTime frame
Heart rate, mean arterial pressure (MAP), blood oxygen saturation, BIS value of the two groups of patients at different time points.;40-item Recovery Quality Scale score;

Countries

China

Contacts

Public ContactYang Maiqiao

Yan'an Hospital of Kunming City

1690726990@qq.com+86 138 8871 7397

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026